Current Active Studies

A multicentre health services program funded by the Victoria Department of Health examing inpatient oral penicillin challenge.

Chief Investigator - A/Prof Jason Trubiano

Clinical Lead - Dr Kyra Chua

Clinical Sites - Austin Health and Peter MacCallum Cancer Centre (Melbourne, Australia)

https://www.bettersafercare.vic.gov.au/improvement/projects/mtip/antibiotic-allergy-delabelling

Australian Registry of Severe Cutaneous Adverse Reactions - A national study of SCAR

Chief Invesigator - A/Prof Jason Trubiano

Status - Recruiting

Clinical Sites - Austin Health (Host) 12 ethics approved sites across Australia and New Zealand

Trial registration -  ACTRN12619000241134 https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=376954&isReview=true

Predictors, Immunopathogenesis and Prescribing in Antibiotic allergy

Chief Investigator - A/Prof Jason Trubiano

Status - Recruiting

Clinical Sites - Austin Health and Peter MacCallum Cancer Centre (Melbourne, Australia) 

Institute/Research Sites - Vanderbilt University (USA), Doherty Institute (VIC, AUS), Murdoch University (WA, AUS)

International Collaborators - University of Cape Town (South Africa)

Multicentre observation study of severe antibiotic allergy - examining impacts of antibiotic allergy testing and novel immune diagnostics

A pilot randomised control trial of oral penicillin challenge in the ICU.

PI - Dr Morgan Rose

Status - Recruiting 

Clinical Sites - Austin Health and Royal Melbourne Hospital (Melbourne, Australia)

ANZCTR - https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=379735&isReview=true

A multicentre pilot randomised control trial of oral beta-lactam challenge in the perioperative setting

PI - Dr Joseph Deluca

Status - Recruiting

Clinical Sites - Austin Health, Royal Melbourne Hospital, Alfred Health (Melbourne, Australia)

ANZCTR - https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=380565&isReview=true

An international survey of perioperative drug allergy testing

PI - Dr Joseph Deluca

Status - Recruitment pending

A multicentre phase III study of oral penicillin allergy challenge in the outpatient setting

PI - Dr Ana Copaescu

Status - Recruitment pending

Clinical Sites - Austin Health (AUS), Melbourne Health (AUS), Vanderbilt University (USA), McGill University (Canada - pending)

Trial registration - https://clinicaltrials.gov/ct2/show/NCT04454229

Direct Oral penicillin pRovocAtion in priMary cAre: DIORAMA Study.

A multiple site study of direct oral penicillin challenge in primary care (GP) clinics in Melbourne, Australia.

Ethics approval: HREC/85131/AUSTIN-2022

PI: Kyra Chua

Status: Recruiting

See link below: